Search results for "Bayesian hierarchical modeling"
showing 8 items of 8 documents
VARIABLE SELECTION FOR NOISY DATA APPLIED IN PROTEOMICS
2014
International audience; The paper proposes a variable selection method for pro-teomics. It aims at selecting, among a set of proteins, those (named biomarkers) which enable to discriminate between two groups of individuals (healthy and pathological). To this end, data is available for a cohort of individuals: the biological state and a measurement of concentrations for a list of proteins. The proposed approach is based on a Bayesian hierarchical model for the dependencies between biological and instrumental variables. The optimal selection function minimizes the Bayesian risk, that is to say the selected set of variables maximizes the posterior probability. The two main contributions are: (…
Bayesian Methodology in Statistics
2009
Bayesian methods provide a complete paradigm for statistical inference under uncertainty. These may be derived from an axiomatic system and provide a coherent methodology which makes it possible to incorporate relevant initial information, and which solves many of the difficulties that frequentist methods are known to face. If no prior information is to be assumed, the more frequent situation met in scientific reporting, a formal initial prior function, the reference prior, mathematically derived from the assumed model, is used; this leads to objective Bayesian methods, objective in the precise sense that their results, like frequentist results, only depend on the assumed model and the data…
A Bayesian unified framework for risk estimation and cluster identification in small area health data analysis.
2020
Many statistical models have been proposed to analyse small area disease data with the aim of describing spatial variation in disease risk. In this paper, we propose a Bayesian hierarchical model that simultaneously allows for risk estimation and cluster identification. Our model formulation assumes that there is an unknown number of risk classes and small areas are assigned to a risk class by means of independent allocation variables. Therefore, areas within each cluster are assumed to share a common risk but they may be geographically separated. The posterior distribution of the parameter representing the number of risk classes is estimated using a novel procedure that combines its prior …
A novel approach to quantifying the sensitivity of current and future cosmological datasets to the neutrino mass ordering through Bayesian hierarchic…
2017
We present a novel approach to derive constraints on neutrino masses from cosmological data, while taking into account our ignorance of the neutrino mass ordering. We derive constraints from a combination of current and future cosmological datasets on the total neutrino mass $M_\nu$ and on the mass fractions carried by each of the mass eigenstates, after marginalizing over the (unknown) neutrino mass ordering, either normal (NH) or inverted (IH). The bounds take therefore into account the uncertainty related to our ignorance of the mass hierarchy. This novel approach is carried out in the framework of Bayesian analysis of a typical hierarchical problem. In this context, the choice of the ne…
What Bayesians Expect of Each Other
1991
Abstract Our goal is to study general properties of one Bayesian's subjective beliefs about the behavior of another Bayesian's subjective beliefs. We consider two Bayesians, A and B, who have different subjective distributions for a parameter θ, and study Bayesian A's expectation of Bayesian B's posterior distribution for θ given some data Y. We show that when θ can take only two values, Bayesian A always expects Bayesian B's posterior distribution to lie between the prior distributions of A and B. Conditions are given under which a similar result holds for an arbitrary real-valued parameter θ. For a vector parameter θ we present useful expressions for the mean vector and covariance matrix …
Learning Bayesian Metanetworks from Data with Multilevel Uncertainty
2006
Managing knowledge by maintaining it according to dynamic context is among the basic abilities of a knowledge-based system. The two main challenges in managing context in Bayesian networks are the introduction of contextual (in)dependence and Bayesian multinets. We are presenting one possible implementation of a context sensitive Bayesian multinet-the Bayesian Metanetwork, which implies that interoperability between component Bayesian networks (valid in different contexts) can be also modelled by another Bayesian network. The general concepts and two kinds of such Metanetwork models are considered. The main focus of this paper is learning procedure for Bayesian Metanetworks.
Natural induction: An objective bayesian approach
2009
The statistical analysis of a sample taken from a finite population is a classic problem for which no generally accepted objective Bayesian results seem to exist. Bayesian solutions to this problem may be very sensitive to the choice of the prior, and there is no consensus as to the appropriate prior to use.